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NR2E3 Polyclonal Antibody, 50ul Microplate Mixer An important paralog of RNF144B

SKU: 17192701334

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NR2E3 Polyclonal Antibody, 50ul Microplate Mixer An important paralog of RNF144BThis protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have been shown to regulate pathways involved in embryonic development, as well as in maintenance of proper cell function in adults. Members of this family are characterized by discrete domains that function in DNA and ligand binding. This gene encodes a retinal nuclear receptor that is a ligand dependent transcription

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Description

An important paralog of RNF144B is RNF19A

The receptor functions as a neurotransmitter-gated ion channel

mutation screening in breast cancer pedigrees and in sporadic tumors was negative

and the encoded protein may be involved in the regulation of glucose and lipid metabolism

Mutations in CEP41 have been associated with Joubert Syndrome 15

NR2E3 Polyclonal Antibody, 50ul Microplate Mixer An important paralog of RNF144BThis protein is part of a large family of nuclear receptor transcription factors involved in signaling pathways. Nuclear receptors have been shown to regulate pathways involved in embryonic development, as well as in maintenance of proper cell function in adults. Members of this family are characterized by discrete domains that function in DNA and ligand binding. This gene encodes a retinal nuclear receptor that is a ligand dependent transcription

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