Human C-X-C Chemokine Receptor Type 3, CXCR3 ELISA Kit, 96T Enzyme Activity Assays insulin-dependent diabetes mellitus
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Human C-X-C Chemokine Receptor Type 3, CXCR3 ELISA Kit, 96T Enzyme Activity Assays insulin-dependent diabetes mellitus[Isoform 1]: Receptor for the C X C chemokine CXCL9, CXCL10 and CXCL11 and mediates the proliferation, survival and angiogenic activity of human mesangial cells (HMC) through a heterotrimeric G protein signaling pathway (PubMed: 12782716). Binds to CCL21. Probably promotes cell chemotaxis response. [Isoform 2]: Receptor for the C X C chemokine CXCL4 and also mediates the inhibitory activities of CXCL9, CXCL10 and CXCL11 on the proliferation, survival
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