PF-04449913 0077 4-benzodiazonin-3-one

4-benzodiazonin-3-one

Solubility: DMSO: 100 mg/mL(136

Pimecrolimus is an immunomodulating agent used in the treatment of atopic dermatitis (eczema)

AG 1749 sodium

InChi: InChI=1S/C19H28N2O4

PF-04449913 0077 4-benzodiazonin-3-oneGlasdegib, also known as PF 04449913, is an orally bioavailable small molecule inhibitor of the Hedgehog (Hh) signaling pathway with potential antineoplastic activity. Hedgehog inhibitor PF 04449913 appears to inhibit Hh pathway signaling. The Hh signaling pathway plays an important role in cellular growth, differentiation and repair. Constitutive activation of Hh pathway signaling has been observed in various types of malignancies. Product